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UPDATE: Pfizer and BioNTech Covid-19 vaccine candidate is “strongly effective”

The Thaiger

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UPDATE: Pfizer and BioNTech Covid-19 vaccine candidate is “strongly effective” | The Thaiger
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Pfizer is claiming that it’s current Covid-19 vaccine candidate “may be 90% effective” at preventing infection from the coronavirus. The pharmaceutical company says later this month they could be ready to file an ’emergency use’ application with US regulators.

US-based Pfizer and its German partner BioNTech are claiming that their vaccine against Covid-19 was “strongly effective” and has “exceeded expectations” with results that are likely to be met with cautious excitement amidst the global pandemic.

The vaccine trial is the first in the US to generate late-stage data. During yesterday’s announcement the companies claimed that early analysis of the results indicated that individuals who received 2 injections of the vaccine, 3 weeks apart, experienced more than 90% fewer cases of symptomatic Covid-19 than those on the placebo. Phase 3 study is ongoing and new late-stage data could affect the final results.

The companies won’t be filing for an emergency-use authorisation, to more broadly distribute the vaccine, until they reach another milestone… when half the patients in their study have been observed “for any safety issues for at least 2 months following their second dose”. The companies say they should reach that stage in the 3rd or 4th week of this month.

The vaccine developed by Pfizer and its German partner BioNTech are among 10 current vaccine candidates in third-stage testing around the world. Another US company, Moderna, has also speculated that it should be able to file an application with the US FDA later this month.

Volunteers in the 3rd-stage trials don’t know who is receiving the real vaccine and who is getting the placebo vaccine. To maintain transparency, the research teams are also kept in the dark as to who is receiving the candidate vaccine. No participant so far has become severely ill, according to yesterday’s latest information.

Participants were tested only if they developed symptoms, leaving the question unanswered whether vaccinated people could become infected “but show no symptoms and unknowingly spread the virus”.

Although the development provides a glimmer of hope in the battle against the Covid-19 pandemic, and a triumph for Pfizer and BioNTech, key information about the vaccine has not been shared at this stage; no information if the vaccine can prevent severe cases that cause hospitalisation and death, or whether it protects those people, without symptoms, from carrying the virus.

The interim test data, from an independent data monitoring board, looked at 94 infections recorded so far in a study that has enrolled nearly 44,000 people in the US and 5 other countries.

But officials say, despite the development, that it’s unlikely any vaccine could be cleared for a wider roll-out before the end of the year, and that initially there will be limited supplies. Then there will be an even longer time before a successful vaccine will have a major effect on total infections, plus the public education battle.

The US FDA’s scientific consultants say that they worry that allowing emergency use of a Covid-19 vaccine “could damage confidence in the vaccines” and make it harder to ever find out how well they really work.

“It’s critical these massive studies are allowed to run to completion.”

Both Pfizer’s vaccine and Moderna’s use messenger-RNA, or mRNA, vaccine technology, using genetic material to cause the body to create a protein from the virus. The host’s immune system then recognises the virus and learns to attack. Other vaccines in the late stages of development use genetically engineered viruses for a similar purpose, or pieces of protein that are directly injected. No mRNA product has ever been approved by regulators.

Of the 7 coronaviruses (229E, NL63, OC43, HKU1, MERS-CoV, SARS-CoV and SARS-CoV-2 aka. Covid-19) there has never been a successful vaccine developed.

Meanwhile, Brazil’s National Health Surveillance Agency is suspending its Phase 3 clinical trials of a Chinese-developed Covid-19 vaccine following an “adverse incident” involving a volunteer. The report was from CNN Brasil.

CoronaVac, developed by Chinese pharmaceutical company Sinovac Biotech, began phase 3 trials of CoronaVac in collaboration with the Brazilian Butantan Institute in Sao Paulo in late July. The studies were suspended due to the “occurrence of serious adverse events in one of the volunteers in Brazil.”

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10 Comments

10 Comments

  1. Avatar

    Ynwaps

    November 10, 2020 at 10:34 am

    Guess this is because all quick tests are incredibly inaccurate?

    “Participants were tested only if they developed symptoms, leaving the question unanswered whether vaccinated people could become infected “but show no symptoms and unknowingly spread the virus”.”

    • Avatar

      clfeige

      November 16, 2020 at 10:29 am

      NO. the article explained why they didn’t …couldn’t do it. there’s no need to reinterpret what was said into something that was not said.

  2. Avatar

    Don R

    November 10, 2020 at 12:57 pm

    I could care less if the vaccine is a placebo. In fact, they might wanna try that. Just spray water up everyone’s nose and tell em it’s a vaccine. POOF! Virus gone. Suddenly people will be dying of cancer and heart attacks again.

  3. Avatar

    Issan John

    November 10, 2020 at 1:23 pm

    The general scientific consensus seems very clearly to be that rushing to conclusions and into mass vaccinations would be a mistake, pushed by politicians desperate to not only get things back to “normal” but to be seen to get things back to normal.

    With the efforts being put into a vaccine it’s perfectly possible one may be found that is 90 to 100% effective – some vaccines are, and just because one hasn’t been found before for a corona virus doesn’t mean that it won’t happen now. Until then , there’s no practical option but to make the best of it, balancing the options, rather than just pretending it’s not happening.

    • Avatar

      paul scott

      November 10, 2020 at 2:38 pm

      OK you take the vaccine. We want all the stupidest people to be vaccinated. That way the civil war will be easier.

      • Avatar

        SG666

        November 11, 2020 at 10:00 am

        Agree 100 percent. To keep it simple, at the moment somebody will come close to my family with a needle the person should be ready to get a bullet between his or her eyes.

    • Avatar

      chris

      November 16, 2020 at 10:35 am

      your comment doesn’t make sense because it’s focused on an irrelevant point. None of the testing phases have been skipped and that quite literally is what is meant by “rushing to conclusions”. If you had more detail then “rushing to conclusions” would be worded something like “skipping clinical trials” and no clinical trials have been skipped here.

  4. Avatar

    paul scott

    November 10, 2020 at 2:36 pm

    All the brain dead people who voted for Biden, and who are not already physically completely dead, should take this vaccine.

  5. Avatar

    Ameila Leary

    November 11, 2020 at 1:21 pm

    That is positive news and that can’t be seen from a political point of view. It is also tentative and the final result will be influenced by further tests in all phases of development. We hope you will be successful! Phenomenal work, everything. Well done to all the scientists and researchers who took part in this experiment, as well as the move toward lethal infection relief.

  6. Avatar

    AI

    November 12, 2020 at 3:21 pm

    I don’t know any of you and will probably never meet you, but folks, you’d better damn sure check what the ingredients are and then run them one by one in a good search engine (not GO – OGLE), and also if the company producing it is offering liability for any damages which it will create later on.
    Watch the film ‘Vaxed’ and part Vaxed II – if you can still find it online. It had been banned by the usual suspects.

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Coronavirus (Covid-19)

6 more Thai women test positive for Covid-19 after returning from Myanmar, skipping quarantine

Caitlin Ashworth

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6 more Thai women test positive for Covid-19 after returning from Myanmar, skipping quarantine | The Thaiger
PHOTO: Line Today

6 more Thai women, who crossed the Myanmar border into Chiang Rai, have tested positive for Covid-19, according to the Public Health Ministry. 4 other Thai women in Chiang Mai and Chiang Rai recently tested positive after returning from Myanmar’s Tachileik district. All 10 women evaded the mandatory 14 quarantine.

Some cases trace back to the 1G1 hotel and entertainment venue in Tachileik where some of the women confirm that they worked, stayed or visited. Some women said they worked at hotels or bars in Tachileik, but reports do not name the establishments.

Case 1

A 28 year old woman went to work at the 1G1 venue in early November and returned on November 27. A motorbike driver picked her up at the border and took her to the Chiang Rai’s Mae Sai district bus station. She then took a bus back to her home in Phayao.

She went grocery shopping, out to restaurants and to a beer garden. She drove to Chiang Mai and tested positive for Covid-19 on November 30 at a private hospital. She returned to her hometown to be treated at the Phayao Hospital.

Case 2 & 3

After crossing the Thai-Myanmar border on November 28, a 21 year old and 25 year old flew from Chiang Rai to Bangkok’s Don Mueang Airport. The 25 year old then flew to Phichit to visit a friend where she went to local bars. The 21 year old tested positive for Covid-19 yesterday.

Following her friend’s positive result, the 25 year old was “caught” an taken to a quarantine facility where she tested positive, according to Nation Thailand.

Case 4

A 36 year old travelled to Tachileik on November 3 and visited the 1G1 entertainment venue on November 23 and 24. A couple days later, she developed symptoms of a cough, runny nose and body ache. She treated her symptoms with over the counter drugs and crossed the natural border into Thailand on November 30 with help from a Myanmar national.

The woman travelled to Chiang Mai and then took a flight to Bangkok’s Don Mueang Airport. She took a taxi form the airport to the Mo Chit Bus Terminal and then took a bus to Ratchaburi.

After hearing about a friend tested positive for Covid-19, the woman went to a local hospital and tested positive for the virus today.

Cases 5 & 6

A 23 year old and a 35 year old worked in Tachileik and returned to Thailand on November 24. They travelled to Chiang Mai and then went to their home in Tak’s Mae Sot district.

After hearing about a friend testing positive, the women got tested and the results came out positive for Covid-19.

Previous local Covid-19 cases

A woman in Chiang Mai and 3 other women in Chiang Rai tested positive for Covid-19 after working in Tachileik. They allegedly entered Thailand illegally, dodging the mandatory 14 day quarantine.

The women could face charges for entering Thailand illegally and violating the Emergency Decree. Public Health Minister Anutin Charnvirakul says he’s asked authorities to press charges “to the fullest extent of the law.”

SOURCE: Nation Thailand

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17 new Covid-19 cases detected in quarantine

Caitlin Ashworth

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17 new Covid-19 cases detected in quarantine | The Thaiger

17 new Covid-19 cases were detected in quarantine, according to the Centre for Covid-19 Situation Administration. The total number of confirmed Covid-19 cases is raised to 4,026 with 3,822 recoveries and 60 deaths. 144 people are currently receiving medical treatment for the coronavirus.

  • A 56 year old Thai woman travelling from Turkey tested positive for Covid-19. She arrived on November 17 and tested positive 5 days later while at an alternative state quarantine facility.
  • A 53 year old Thai man travelling from Kuwait tested positive for Covid-19. He arrived on November 17 and tested positive 3 days later while at a Chon Buri quarantine hotel.
  • A 24 year old Thai woman travelling from Germany tested positive for Covid-19. She arrived on November 19 and tested positive 11 days later while at a Bangkok quarantine hotel.
  • A 44 year old Egyptian man tested positive for Covid-19. He arrived on November 24 and tested positive 5 days later at a quarantine hotel in Samut Prakan.
  • A 31 year old Thai man travelling from Israel tested positive for Covid-19. He returned on November 25 and tested positive 5 days later at a Bangkok quarantine hotel.
  • 2 Thai nationals travelling from Japan tested positive for Covid-19. The 24 year old man and 29 year old woman arrived on November 25 and tested positive 4 days later at a Chon Buri quarantine hotel.
  • A 32 year old Thai woman travelling from Sweden tested positive for Covid-19. She arrived on November 26 and tested positive 4 days later while at Bangkok quarantine hotel.
  • A 57 year old Sudanese woman tested positive for Covid-19. She arrived on November 30 and tested positive the same day after checking in to a alternative hospital quarantine in Bangkok.
  • 5 Thai nationals, ages 26, 31 and 56, travelling from Switzerland tested positive for Covid-19. They arrived on November 25 and tested positive 4 days later while at a state quarantine facility in Chon Buri.
  • A 69 year old Thai man travelling from the United States tested positive for Covid-19. He arrived on November 29 and tested positive the same day after checking in to a hotel quarantine in Bangkok.
  • 2 Thai nationals, ages 43 and 33, travelling from Myanmar tested positive for Covid-19. They arrived on November 24 and tested positive 4 and 5 days later while at a hotel quarantine in Bangkok.
17 new Covid-19 cases detected in quarantine | News by The Thaiger

Daily new Covid-19 cases in Thailand as of December 1, according to Worldometers.

SOURCE: Nation Thailand

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97 police officers investigated for fiddling Covid-19 payments

Maya Taylor

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97 police officers investigated for fiddling Covid-19 payments | The Thaiger
PHOTO: www.newsbeezer.com

97 police officers, from 41 police stations, are currently being investigated for an alleged scam involving Covid-19 payments meant for officers who worked extra shifts during the crisis. The case was assigned by national police chief Suwat Jangyodsuk in November, when it came to light that some officers may have fraudulently claimed allowances meant for others.

In one incident, an officer responsible for transferring extra payments to police on the southern island of Phuket transferred the money to his own accountant instead. At the time, the transfer was dismissed as a mistake (in his favour), with the officer in question receiving a warning, and payments then made to the qualifying officers.

Wissanu Prasatthong-Osot from the National Internal Affairs Police says the investigation should reach a conclusion within the next 10 days.

“The result of the investigation should be ready in 10 days. Currently, 97 officers in 41 police stations ranging from non-commissioned to generals are under investigation for being involved in the swindle. The bureau aims to provide justice to all policemen involved. After the investigation concludes, the victims will receive their full allowance, while the offending officers will be punished under the law and disciplinary standards.”

Nation Thailand reports that a full list of alleged offenders has been sent to Suwat, with Wissanu promising that none will escape prosecution.

“The National Police chief had also ordered the transfer of offending officers at the commander and sub-commander levels out of their areas as per the investigation procedures.”

SOURCE: Nation Thailand

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