Connect with us

Coronavirus (Covid-19)

Covid-19 is capable of infecting the brain – Yale study

Published

 on 

FILE PHOTO

A new paper from a time at Yale University, Connecticut, in the US, says that headaches, confusion and delirium experienced by some Covid-19 patients may be the result of the coronavirus directly invading the brain. The preliminary research offers several some additional evidence to support earlier untested theories about long-term effects on some Covid-19 patients.

The novel coronavirus not only targets the lungs (a situation that is now well documented), but also the kidneys, liver and blood vessels. And brain. About 50% of patients report neurological symptoms suggesting the virus is also attacking the brain.

The study, led by Yale immunologist Akiko Iwasaki, reported that the virus is able to replicate inside the brain, and can starve brain cells of oxygen, though the precise mechanisms or prevalence of the phenomenon is not currently clear.

“If the brain does become infected, it could have a lethal consequence.”

Several peer researchers have already commented that the study, released yesterday, was “careful and elegant”, showing in multiple ways that the virus can infect a patient’s brain cells.

The Chairman of the neurology department at the University of California, San Francisco, S Andrew Josephson, has praised the techniques used for the study, but added that he would “remain cautious” until the paper underwent peer review.

“Understanding whether or not there is direct viral involvement of the brain is extraordinarily important.”

Doctors have previously believed that the neurological impacts seen in about half of all Covid-19 patients could instead be the result of an abnormal immune response that causes inflammation of the brain, part of the “cytokine storm”, rather than the virus invading directly.

The Yale experiments approached the question by infecting lab-grown mini-brains known as “brain organoids”, by infecting mice, and by examining the brain tissues of deceased Covid-19 patients. The team discovered that the SARS-CoV-2 virus is able to infect brain neurons and then “hijack” the neuron cell’s machinery and make copies of itself.

“Infected cells in turn promoted the death of surrounding cells by choking their oxygen supply”, according to the report.

They also performed a spinal tap on a Covid-19 patient suffering from delirium finding the individual had neutralising antibodies against the virus in their spinal fluid. They also examined the brains of 3 patients who died from Covid-19 related complications, finding evidence of the virus in the brains of the patients.

“The infected regions did not show signs of having been infiltrated by immune cells, such as T-cells, which rush to the site of other viruses like Zika or herpes to kill the infected cells.”

The report suggested that this could hint that the overloaded immune response known as cytokine storm which is responsible for much of the damage seen in the lungs of Covid-19 patients, might not be the main cause of neurological symptoms.

Researchers believe that the virus may be getting into the brain through the nose, or through the eyes or even from the bloodstream.

“It’s unclear which route the pathogen is taking, and whether it does so often enough to explain the symptoms seen in people.”

SOURCE: AFP | New York Times

 

Get more from The Thaiger

Join the conversation and have your say on Thailand news published on The Thaiger.

Thaiger Talk is our new Thaiger Community where you can join the discussion on everything happening in Thailand right now.

Please note that articles are not posted to the forum instantly and can take up to 20 min before being visible. Click for more information and the Thaiger Talk Guidelines.

If you have story ideas, a restaurant to review, an event to cover or an issue to discuss, contact The Thaiger editorial staff.

Follow Thaiger by email:

What you get for $X4 hours ago

What $100,000 buys you for a condo in Bangkok, Phuket, Pattaya, Koh Samui and Hua Hin

Thailand5 hours ago

Thailand News Today | Activists plan protests all across Thailand

Thailand6 hours ago

Snitching on parking space hoggers could earn you 5,000 baht in Thailand

Sponsored14 hours ago

10 Best Seed Banks that Ship Cannabis Seeds Discreetly to You (Free US Shipping)

Weather6 hours ago

Storm Noru weakens from typhoon to depression as it moves across Thailand

World7 hours ago

Suicide bombing in Afghanistan hits students preparing for exam

Politics7 hours ago

BREAKING: Prayut reinstated as Prime Minister of Thailand

Join the conversation on the Thaiger Talk forums today!
Technology8 hours ago

What role for Thailand in China’s great European EV invasion?

Cambodia8 hours ago

Cambodian delegation in UK to seach for stolen treasures

Thailand8 hours ago

20 baht notes printed with errors, says Bank of Thailand

Crime8 hours ago

Loan shark bombs debtor’s house in southern Thailand

Thailand9 hours ago

Thai researchers develop flood-resistant rice strain

Press Room9 hours ago

Southeast Asia’s hospitality leaders step into the ring to fight for sustainability at PHIST 5

Crime9 hours ago

Horrified relatives attempt ID of disfigured suitcase victim

Travel9 hours ago

Things to do in Bangkok that cost next to nothing (2022)

Travel10 hours ago

5 best spa treatments in Bangkok to pamper yourself this September – October

Thailand1 year ago

Morning Top Stories Thailand | Police to end protests, Human Trafficking | September 14

Thailand2 years ago

Thailand News Today | Thai Airways in rehab, All go for Songkran | March 4

Tourism2 years ago

Phuket’s nightlife. Yes, bars and clubs are still open | VIDEO

Phuket2 years ago

Thailand News Today | Covid passport talks, Thai Airways heads to court | March 2

Tourism2 years ago

Phuket Thai food treats you need to try | VIDEO

Thailand2 years ago

Thailand News Today | Bars, pubs and restaurants ‘sort of’ back to normal | Feb 23

Tourism2 years ago

In search of Cat & Dog Cafés in Phuket Town | VIDEO

Thailand2 years ago

Thailand News Today | Gambling crackdown, Seafood market to reopen, Vlogger challenge | Jan 21

Thailand2 years ago

Thailand News Today | Covid testing for visas, Business impact, Vaccine approval | January 19

Thailand2 years ago

Thailand News Today | Weekend Bangkok bombs, Thailand fires, Covid update | January 18

Thailand2 years ago

Thailand News Today | Stray car on runway, Indonesian quake, 300 baht tourist fee | January 15

Thailand2 years ago

Thailand News Today | Governor off respirator, sex-trafficking arrest, condo prices falling | January 14

Thailand2 years ago

Thailand News Today | Chinese vaccine, Thailand ‘drug hub’, Covid update | January 13

Thailand2 years ago

Thailand News Today | Bangkok may ease restrictions, Phuket bar curfew, Vaccine roll out | January 12

Thailand2 years ago

Thailand News Today | Covid latest, Cockfights closed down, Bryde’s Whale beached | January 11

Trending