Connect with us

Coronavirus (Covid-19)

Singapore to begin human trial of potential Covid-19 prophylactic

Jack Burton

Published

 on 

PHOTO: Straits Times

A new drug, currently known as TY027, might be used to protect frontline healthcare workers against potential exposure to Covid-19, or travellers when they head to countries with high community transmission. Next week, 23 volunteers in Singapore will be involved in a clinical safety trial for the prophylactic antibody drug, which could be a viable treatment the disease that has already killed more than 400,000 around the globe.

The co-founder of Tychan, the biotech company behind the drug, told the media that if trials are successful, it could be used to render temporary protection against infection, as antibody drugs tend to be effective for about 2-3 weeks per dose. Using the drug to treat confirmed cases “could reduce a lot of problems we face right now,” such as the limited number of ventilators available at hospitals.

“One obvious thing is that a lot of the patients get sick for a very long time, and some of them even get very severe respiratory disease, so much so that you need oxygen ventilators to help them tie through this critical period, without which they would die. We hope this treatment will reduce the number of people who go into such a severe stage, and hopefully the number of people who die from Covid-19 can be kept to a minimum.”

But he noted that the eventual use of the drug, and who it will be administered to, will depend on the outcome of the Phase 1 clinical safety trial, which will take about 6 weeks. Singapore’s Health Sciences Authority granted approval for the trial on Monday. The trial, which will be conducted by SingHealth’s investigational medicine unit, will focus on evaluating the safety, tolerability and “pharmacokinetics,” the way the body reacts to the drug. If proven safe the drug will still have to undergo more tests before it can be used in real-life clinical settings, and that process could take months.

This is the first time an in-human trial for a Covid-19 treatment has been approved in Singapore. Presently, there is no proven antibody-based treatment for Covid-19, nor any licensed vaccine.

Tychan said in a statement that it produced the antibody on February 25, in partnership with Singpore’s Ministry of Defence, the Ministry of Health, the Economic Development Board and other government agencies as part of a whole-of-government collaborative effort. The company then identified it as the most promising among several antibodies that demonstrated 100% neutralisation against Covid-19. Since then, preclinical safety studies and other regulatory requirements, including a 3 week stability test, have been completed successfully.

SOURCE: SOURCE: Bangkok Post

 

Get more from The Thaiger

📱 Download our app on Android or iOS
👋 Have your say on our Thailand forums
🔔 Subscribe to our daily email newsletter
📺 Subscribe / Join YouTube for daily shows
👍 Like/Follow us on Facebook
🐦 FOLLOW us on Twitter
📷 FOLLOW us on Instagram

image

Join the conversation and have your say on Thailand news published on The Thaiger.

Thaiger Talk is our new Thaiger Community where you can join the discussion on everything happening in Thailand right now.

Please note that articles are not posted to the forum instantly and can take up to 20 min before being visible. Click for more information and the Thaiger Talk Guidelines.

1 Comment

1 Comment

  1. Avatar

    Kelvin

    Thursday, June 11, 2020 at 11:59 am

    the question is how is this stuff made

    seems like they are all rushing to market at the expense of man kind

    we need to know more before they let the genie out

Leave a Reply

Your email address will not be published. Required fields are marked *

Jack Burton is an American writer, broadcaster, linguist and journalist who has lived in Asia since 1987. A native of the state of Georgia, he attended the The University of Georgia's Henry Grady School of Journalism, which hands out journalism's prestigious Peabody Awards. His works have appeared in The China Post, The South China Morning Post, The International Herald Tribune and many magazines throughout Asia and the world. He is fluent in Mandarin and has appeared on television and radio for decades in Taiwan, Mainland China, Hong Kong and Macau.

Follow Thaiger by email:

Transport4 hours ago

August flight plans: Bangkok Airways, Nok Air, Thai Lion

Coronavirus (Covid-19)5 hours ago

New site for foreigner vaccine; Mor Prom deletes appointments

Politics7 hours ago

Facebook fake news post suggesting a coup faces prosecution

Welcome back to Thailand!

Thaiger is getting behind local businesses for the restart of tourism in Thailand - up to 50% discounts across all advertising packages!

Koh Samui11 hours ago

UPDATED: Samui Covid-19: 14 new Black Club infections, 2nd small cluster

Thailand12 hours ago

40,000 cases a day could happen by September, says projection

Phuket12 hours ago

Phuket Sandbox Covid-19 infections: 35 today, 209 this week

image
Join the conversation on the Thaiger Talk forums today!
Thailand13 hours ago

Prayut says he will not resign, warns politicians to behave

Thailand14 hours ago

Bangkok Train market to possibly close for good

Coronavirus (Covid-19)14 hours ago

Border between Kanchanaburi and Myanmar closed until…

Thailand15 hours ago

Covid UPDATE: 18,912 infections, provincial totals

Coronavirus (Covid-19)15 hours ago

PCD says don’t throw away used masks in water bottles after infections linked to bottles

Thailand17 hours ago

Government says it’s okay to criticise them, if it’s fact based

Thailand18 hours ago

Bangkok volunteer group “Sai Mai Will Survive” overwhelmed with calls

Coronavirus (Covid-19)18 hours ago

Phuket reservations slow down for August

Thailand22 hours ago

Covid UPDATE Saturday: 18,912 infections, news briefs

Thailand5 months ago

Thailand News Today | Thai Airways in rehab, All go for Songkran | March 4

Tourism5 months ago

Phuket’s nightlife. Yes, bars and clubs are still open | VIDEO

Phuket5 months ago

Thailand News Today | Covid passport talks, Thai Airways heads to court | March 2

Tourism5 months ago

Phuket Thai food treats you need to try | VIDEO

Thailand5 months ago

Thailand News Today | Bars, pubs and restaurants ‘sort of’ back to normal | Feb 23

Tourism5 months ago

In search of Cat & Dog Cafés in Phuket Town | VIDEO

Thailand6 months ago

Thailand News Today | Gambling crackdown, Seafood market to reopen, Vlogger challenge | Jan 21

Thailand6 months ago

Thailand News Today | Covid testing for visas, Business impact, Vaccine approval | January 19

Thailand6 months ago

Thailand News Today | Weekend Bangkok bombs, Thailand fires, Covid update | January 18

Thailand7 months ago

Thailand News Today | Stray car on runway, Indonesian quake, 300 baht tourist fee | January 15

Thailand7 months ago

Thailand News Today | Governor off respirator, sex-trafficking arrest, condo prices falling | January 14

Thailand7 months ago

Thailand News Today | Chinese vaccine, Thailand ‘drug hub’, Covid update | January 13

Thailand7 months ago

Thailand News Today | Bangkok may ease restrictions, Phuket bar curfew, Vaccine roll out | January 12

Thailand7 months ago

Thailand News Today | Covid latest, Cockfights closed down, Bryde’s Whale beached | January 11

Thailand7 months ago

Thailand News Today | Southern floods, Face mask fines, Thai Air Asia woes | January 8

Trending