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Coronavirus (Covid-19)

2 Covid vaccine trials halted in phase 3 over safety concerns

Maya Taylor

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PHOTO: Medical Xpress

After Johnson & Johnson paused phase 3 of its Covid vaccine trials due to safety concerns, a second pharmaceutical company has followed suit. Eli Lilly has halted phase 3 trials of a lab-produced antibody treatment, 24 hours after the Johnson & Johnson decision. The Bangkok Post reports that an unspecified incident led Eli Lilly to call a temporary halt to the trials. The day before, Johnson & Johnson paused its phase 3 trials after a participant fell ill. A spokesperson for J&J says the hiatus is temporary.

The 2 delays follow a similar incident with phase 3 trials of a vaccine being jointly worked on by Oxford University and Astra Zeneca, which was briefly delayed last month due to an unexplained illness in one participant. Trials of that vaccine have now resumed globally, with the exception of the US, for reasons unknown. Such snags are par for the course in the final phase testing of vaccine development, particularly as the number of participants is increased significantly to see if very rare side-effects are presented.

A spokesperson for Eli Lilly says the company backs the Data Safety and Monitoring Board in calling a temporary halt to phase 3 trials.

“Lilly is supportive of the decision by the independent DSMB to cautiously ensure the safety of the patients participating in this study.”

Eli Lilly’s trial began in August, aimed at recruiting 10,000 participants, across 50 sites, including the US, Denmark and Singapore, using a lab-produced antibody treatment, similar to that developed by Regeneron and used to treat US President Donald Trump recently. Eli Lilly has not given any further information about the safety concern which has paused phase 3.

Meanwhile, a J&J spokesman says such breaks are to be expected in large-scale trials and that reported illnesses or side-effects may be unrelated to the vaccine.

“It’s not at all unusual for unexpected illnesses in large studies over their duration. In some cases, serious adverse events may have something or nothing to do with the drug or vaccine being investigated.”

SOURCE: Bangkok Post

 

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3 Comments

3 Comments

  1. Avatar

    Al

    Wednesday, October 14, 2020 at 9:44 pm

    Before anyone takes any vaccine, you really should be able to view the ingredients and whether or not the company who are providing it are liable for any after effects. If they aren’t liable, then you should also ask why?
    Simple as that!

    • Avatar

      Paul Douglas McCarty

      Tuesday, October 27, 2020 at 10:32 pm

      Agree!

  2. Avatar

    Don R

    Thursday, October 15, 2020 at 5:38 pm

    The West will have herd immunity long before any vaccine is widely distributed. The hardest hit countries are already almost there.

    It will be nice to return to normal. It will be years before Asia returns to normal. Just this week I spoke with a Thai guy who compared covid to HIV: No chance of immunity, no chance of vaccine, it’s a death sentence, even if you survive you’ll be a carrier and just get reinfected … Where do you think he got these ideas? Certainly not from our *outstanding* news media!

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Thailand

Americans in Thailand urge US to provide Covid-19 vaccines to citizens overseas

Tanutam Thawan

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Stock photo by Mufid Majnun for Unsplash

Thai officials say expats living in Thailand will be included in the government’s mass Covid-19 vaccination plan, but exactly when that will be is still up in the air. With foreign embassies in Thailand clearly stating that they will not assist with providing citizens living overseas with vaccines, expats are relying on the Thai government.

A number of Americans are now urging the US government to provide Covid-19 vaccines to citizens living in Thailand. And with the recent outbreak linked to the more contagious variant of the virus, getting a vaccine in Thailand has become more pressing.

A “Covid-19 Vaccine Task Force” of Democrats Abroad Thailand members, as well as those from American organisations based in Thailand, is calling on the US government to deliver vaccines to citizens living in Thailand, chairperson of Democrats Abroad Thailand and a United Nations consultant, Paul Risley, told VOA.

“Americans who live abroad need to be vaccinated for the same reasons that Americans who live in the United States need to be vaccinated… Because it’s the only way to stop Covid-19.”

If an American were to travel back to the US for a vaccine, they would still need to stay in a hotel or certified facility for a 14-day quarantine at their own expense when re-entering Thailand. Along with getting together the required paperwork, they would need to go through numerous Covid-19 tests including before the flight, upon arrival and before being released from quarantine. The flights to and from the US can end up being more than 20 hours per trip and add up to thousands of dollars in travel costs.

For the vast majority of Americans in Thailand, flying back to the US is the only way to get vaccinated at the moment. The US Embassy in Bangkok says vaccines will not be provided for US citizens living overseas.

The Department of State does not provide direct medical care, including vaccinations, to private U.S. citizens abroad. We are committed to providing all possible consular assistance to U.S. citizens in need overseas, including by providing information on local medical resources when appropriate. Please follow host country developments and guidelines for COVID-19 vaccination.

At a recent Centre for Covid-19 Situation Administration meeting, a spokesperson for the Ministry of Foreign Affairs said “all people who reside in Thailand, regardless of their nationality, are eligible to receive the vaccine under the government’s plan.”

Mass vaccination campaigns are being rolled out in high-risk areas, such as Bangkok’s Khlong Toey slum where a cluster of infections was reported, as well as Phuket and Koh Samui, tourist islands that are said to be of “economic significance.” Health officials are trying to hit herd immunity on the 2 islands to reopen to foreign tourists.

Expats in Phuket who have a valid work permit can now register for a state Covid-19 vaccine. The registration must be under the company name and expats are told to have the company’s human resources staff assist with the registration process.

While no official announcement has been made regarding expats in Koh Samui, some foreigners who work as English teachers on the island say they have received both doses of the Chinese-made Sinovac vaccine. Schools apparently helped with the registration process, but some teachers say they told to keep quiet about getting the vaccine. Some did not receive a vaccine certificate or any other documentation confirming that they are vaccinated against the coronavirus.

SOURCE: VOA

 

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Coronavirus (Covid-19)

Flight booking data shows vaccinations are key to rebooting travel globally

Maya Taylor

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Greece, ready to welcome vaccinated travellers. PHOTO: Flickr/Pedro Szekely

The latest findings from a research firm that analyses flight booking data confirms that vaccination is the key to rebooting international travel. The most recent research from ForwardKeys shows that destinations prepared to welcome vaccinated tourists have seen a surge in bookings.

In particular, Greece and Iceland, have had a significant uptake in inbound flights, while countries where mass vaccination is at an advanced stage, such as Israel, the US and the UK, have seen outbound bookings climb. They key point is that the world’s travel and flight industries are looking to insist on proof of vaccination or vaccine passports for the right to get on an international flight or travel beyond their borders.

Like Thailand, Greece is highly dependent on international tourism. Anxious to revive its decimated economy, the country has announced that tourists who are fully vaccinated, who have a negative Covid-19 test result, or who have recovered from the virus, are welcome to visit. The result is that the country is now the most popular destination among those summer booking holidays from the UK. According to TTR Weekly, confirmed flight bookings between July and September are 12% above what they were at the same time in 2019.

A similar trend can be seen in bookings from the US to Iceland. In March, the Icelandic government confirmed that vaccinated arrivals would face no entry restrictions, which led to a surge in bookings. Flight ticket sales shot up to 158% what they were at the same time in 2019.

Olivier Ponti from ForwardKeys says there is a clear correlation between high vaccination rates and outbound travel. In Israel, which has now vaccinated over 60% of the population, bookings for European trips have reached 63% of what they were in 2019, while in the UK, where over 52% of people are vaccinated, bookings are at 32% of 2019 numbers.

“Vaccinations appear to hold the key to reviving international travel, as countries that make clear promises to welcome vaccinated travellers are being rewarded by strong surges in flight bookings. We see a revival of confidence in outbound travel from countries where there has been a successful rollout of Covid-19 vaccines too.”

SOURCE: TTR Weekly

 

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Coronavirus (Covid-19)

National lockdown in Malaysia as Covid-19 infections surge

Maya Taylor

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PHOTO: Flickr/Dennis Sylvester Hurd

Malaysia has gone into full national lockdown amid a surge in Covid-19 infections, including highly contagious variants that are putting the healthcare system under pressure. According to Thai PBS World, the Malaysian PM, Muhyiddin Yassin, has announced a ban on social gatherings and inter-state and inter-district travel.

“Malaysia is facing a third wave of Covid-19 that could trigger a national crisis.”

Schools and other educational institutions are shut, but Muhyiddin says some economic sectors can continue operating. The lockdown is in force until June 7, with the PM saying the presence of new and highly contagious variants that put pressure on the health system mean there is no other choice.

Malaysia has seen a spike in infections in recent weeks and has now reported 444,484 cases and 1,700 deaths. Yesterday, it reported 3,807 new cases. Last week, the country recorded its first case of the so-called Indian variant, or B.1.617.1, which was found in an Indian national at Kuala Lumpur International Airport. Malaysia remains under the state of emergency introduced in January to curb the spread of the virus.

SOURCE: Thai PBS World

 

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