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Johnson & Johnson Covid-19 vaccine re-approved in the US

Neill Fronde

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FILE PHOTO: The Johnson & Johnson Covid-19 jabs are able to be given in the US again.

The pause on the Johnson & Johnson Covid-19 vaccine was officially lifted in the US yesterday by the Centre For Disease Control And Prevention and the US Food And Drug Administration. They will add a warning label about the risk of blood clots, but vaccination can resume today.

The CDC’s Advisory Committee For Immunization Practices recommended unpausing the Johnson & Johnson vaccine, saying that the benefits outweigh the minimal potential risks. The jab has already been approved for use in Thailand.

The CDC considered several models of possible effects from putting the Johnson & Johnson Covid-19 vaccine back into circulation. They predict 26 to 45 TTS cases but a prevention of 600 to 1,400 Covid-19 deaths and up to 3,500 ICU patients avoided. They believe the vaccine will meet all quality and safety standards and that nervous patience should speak with their healthcare provider.

The CDC director said that she supports the use of the Johnson & Johnson Covid-19 jab for anyone 18 years or older under the FDA emergency use authorisation. Removing 1 of the 3 vaccines Americans are now receiving would slow immunization and herd immunity against Covid-19. Unlike Moderna and Pfizer vaccines, which have not been linked with any blood clots, the Johnson & Johnson jab doesn’t need to be stored in freezing temperatures and is the only 1-shot vaccine, which encourages people that don’t want 2 vaccine appointments.

Blood clots were determined to be exceedingly rare with only 15 possible cases of a rare condition called thrombosis with thrombocytopenia syndrome, and only three deaths amongst people who receive the Johnson & Johnson Covid-19 vaccine. The CDC schedule a phone briefing for medical personnel to discuss the decision and go over symptoms and treatment for TTS. Severe headaches days or weeks after getting the vaccine are the main warning signs.

TTS is an extremely rare type of blood clot that involves an unusual targeting of platelets as your body’s immune system reacts. Antibodies stop the platelets from circulating which causes clotting. An immune product called IVIG can regulate antibodies as treatment, and blood thinners are often helpful as well.

Comparing the half-million deaths in the United States from Covid-19 to the risk of the vaccine causing blood clots, we can analyse several demographics. In 1 million women aged 18 to 49 years old, the Johnson & Johnson Covid-19 vaccine could prevent 12 deaths and over 650 hospitalizations, while the risk of blood clot for that same group is just 7 cases. In a group of 1 million women over 50, nearly 600 deaths and more than 4,700 hospitalizations could be prevented by the vaccine, with the possibility of less than 1 blood clot statistically. As of yet, there haven’t been any blood clot cases amongst men.

Another often overlooked statistic is that while the Johnson & Johnson Covid-19 vaccine carries a low risk of blood clots at just 1.9 cases per million people, Covid-19 itself is a much much bigger cause of blood clots with about 147,000 per million hospitalized Covid-19 patients having blood clots.

The data shows that the blood clots issue is extremely rare, and the positive impact of the Johnson & Johnson jab far outweighs the obscure risk. The ACIP decided against more complicated restrictions for the Johnson & Johnson Covid-19 vaccine mostly based on gender. In the end, they ruled it was suitable for anyone over 18 years old, though 4 members of the committee objected.

The Food And Drug Administration updated their Johnson & Johnson fact sheet for use at vaccination sites, mentioning the minimal blood clot risk in women under 50. Johnson & Johnson themselves had agreed to reword the label to mention TTS. The American Medical Association agreed to disseminate information as well.

SOURCE:CNN

 

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4 Comments

4 Comments

  1. Avatar

    Slugger

    Saturday, April 24, 2021 at 4:34 pm

    TTS, ICU, CDC IVIG, ACIP, why not get some more ‘covid-speak’ in there? Unreadable.

  2. Avatar

    laughing myAoff

    Sunday, April 25, 2021 at 11:05 am

    J&J should just stick to making baby oil

  3. Avatar

    Alavan

    Sunday, April 25, 2021 at 4:39 pm

    “J&J should just stick to making baby oil”
    The Belgian Janssen Pharmaceutica branch of J&J has a big experience with vaccines. They even developed a vaccin against Ebola.
    AstraZeneca, on the other hand, never produced a vaccin before (which can be seen in their problems now). They are good for producing Lidocaine for dental anesthesia.

  4. Avatar

    Ben

    Sunday, April 25, 2021 at 5:22 pm

    The J&J vaccine is good for those that only want one jab. Unless you’re one of the 15 with clotting versus millions that have no side effects.

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Neill is a journalist from the United States with 10 years broadcasting experience and national news and magazine publications. He graduated with a degree in journalism and communications from the University of California and has been living in Thailand since 2014.

Coronavirus (Covid-19)

Friday Covid Update: 2,256 new infections and 30 deaths

Tim Newton

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Thailand’s public health department has reported its tally for the past 24 hours from around the country. There has been 30 new Covid-related deaths and 2,256 new cases. Out of today’s new infection total, 183 of those were from the prison system. Yesterday the numbers jumped substantially because of the release of case numbers from two highly infected prisons – Bangkok Remand Prison and the Central Women’s Correctional Institution.

• Thailand’s Volleyball Association is still hopeful of sending a team to compete in the Nations League in Italy, despite a Custer of cases in the team’s training camp. The TVA has withdrawn the women’s team from the tournament after 22 players and officials tested positive earlier this week. The head of the team announced results of further tests were expected before next Monday.

“We will try to send a team to compete in this event. We hope our athletes are healthy and ready for this competition. If necessary, we may call up some more players.”

• A worker’s camp in Bangkok’s north has been closed by officials after 196 people tested positive for Covid. The new cluster was discovered during proactive testing at the Italian-Thai workers’ camp on Soi Yai Phol, Chalermprakiat Chulabhorn Road in Lak Si, just south of the Don Mueang Airport area.

• After pumping up its numbers for domestic travel for the last quarter of 2021 yesterday, the Tourism Authority of Thailand has now downgraded its outlook for domestic trips and revenues for the rest of this year “because of the economic downturn”.

The TAT governor Yuthasak Supasorn said last year’s 90.5 million domestic trips, supported by the Thai government’s stimulus measures, such as “We Travel Together” and “Tour Teaw Thai” (Travel Around Thailand), have set the bar for expectations this year. But last year’s receipts also include the first 3 months of 2020 which were largely unaffected by the approaching pandemic response and border closures.

Mr. Yuthasak says that the measures could start by the end of June or early July, when the current wave of infections “is hopefully under control”.

SOURCES: FRB | Bangkok Post

 

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Coronavirus (Covid-19)

3 organisers of Phuket’s Kolour superspreader event charged

Neill Fronde

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FILE PHOTO: 3 managers involved in the Kolour superspreader event have been charged.

As Thailand still wrestles to control the third wave of Covid-19, much of which stems from entertainment venues in Bangkok and a massive party in Phuket, Patong police announced that the managers of the Phuket venues that hosted the Kolour superspreader event will be charged under the Emergency Decree. The case report was filed with the public prosecutor yesterday according to the Patong police chief, confirming that 3 people will be prosecuted for the event.

The Kolour Beachside Festival was held April 2 and 3 with events at Café Del Mar Phuket in Kamala, and Shelter Phuket Dance and Night Club and Illuzion Nightclub, both in Patong. Before the festival, Phuket had gone more than a hundred days without any new Covid-19 infections, but by April 7 the Phuket provincial Public Health office announced 8 new infections, half of which had been at the Kolour parties. In the following weeks, officials plead for attendees to be tested as infections spread.

Charges were delayed in being filed to the Phuket Public Prosecutor’s office as a special investigation committee was ordered to be created to oversee the investigation at the request of Region 8’s Police Commander. That committee brought together officials from various law enforcement in the area including the Patong Police, Kamala Police, Phuket Provincial Police, and the Region 8 Police to investigate the Kolour event before anyone was charged.

The manager of Café Del Mar, along with the managing director and the manager of Shelter and Illuzion, which are under the same management team, will be charged for the Kolour festival violating Thailand’s Emergency Decree that was declared to help protect the country from Covid-19 outbreaks. A breach of the Emergency Decree can be held liable for up to 40,000 Baht and 2 years in jail under Section 9 of the Decree.

The latter 2 are also facing charges of operating an unlicensed entertainment venue. This carries the possibility of another year in prison and a fine of up to 60,000 baht, in accordance with Thai Law under Section 26 of the Entertainment Place Act.

SOURCE: The Phuket News

 

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Coronavirus (Covid-19)

Covid-19 patients with high blood pressure at high risk of death -CCSA

Tanutam Thawan

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Stock photo via Bumrungrad Hospital

Covid-19 patients with high blood pressure have the highest risk of death followed by patients infected with the coronavirus who underlying conditions of diabetes or high cholesterol, according to data from Thailand’s Centre for Covid-19 Situation Administration.

Since the start of the pandemic last year, the CCSA has reported 486 coronavirus-related deaths. Out of those fatalities, 392 were reported after April 1. Using data from the recent wave of infections, the CCSA found that those infected with Covid-19 who also have high blood pressure are at the most at risk of death, followed by those who are diabetic and those who have high cholesterol.

Others who are at risk of severe infection or death if infected with Covid-19 include those with chronic kidney disease, heart disease, obesity or lung disease.

Most of the deaths since April 1 have been in Bangkok, making up 46% of the death count in the recent wave, followed and provinces just outside the capital. Most patients who died while infected with Covid-19 have been over 60 years old with underlying health conditions. Several young adults, in their 20s and 30s, who died while infected with Covid-19, had underlying conditions of diabetes and obesity.

Covid-19 patients with high blood pressure at high risk of death -CCSA | News by Thaiger

SOURCE: PR Thai Government

 

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