Chinese mRNA antibody shows promising results for long-term Covid protection
An mRNA antibody therapy developed by Chinese researchers has shown promising results in animal testing, according to a report from the Xinhua news agency. Tests on mice showed the therapy offers long-term protection against Covid-19. The report has been published online in the international journal Cell Research.
Test findings revealed that the neutralising human monoclonal antibody, mRNA-HB27-LNP, provided effective protection against Covid-19 infection in mice for up to 63 days. The antibody was produced on a long-established mRNA-technology platform by researchers from the Suzhou Abogen Biosciences company and the Academy of Military Medical Sciences, a Chinese military medical research institute.
Different doses of the antibody were used in testing, with animals receiving either 1 mg/kg or 0.2 mg/kg. All the mice in these groups survived without developing any clinical symptoms. 80% of animals given 0.04 mg/kg survived, with only minimal or very mild inflammation seen in that group. The treatment has also been shown to offer total protection against the Beta variant of Covid-19 in animals. The 63-day protection against Covid-19 infection is much longer than that seen in traditional protein antibodies, according to the report.
Join the conversation and have your say on Thailand news published on The Thaiger.
Thaiger Talk is our new Thaiger Community where you can join the discussion on everything happening in Thailand right now.
Please note that articles are not posted to the forum instantly and can take up to 20 min before being visible. Click for more information and the Thaiger Talk Guidelines.